University of Pittsburgh

All plenary sessions will be presented in Alumni Hall’s 7th floor lecture hall.

Klaus Hofmann Lecture
Epigenetics at the Intersection of Genes and the Environment in Common Human Disease
4:00 p.m., Friday, 9 October

Andrew P. Feinberg, MD, MPH
King Fahd Professor of Molecular Medicine
Director, Center for Epigenetics
Johns Hopkins University School of Medicine

The research of Andrew P. Feinberg, MD, MPH, has advanced our understanding of the role of epigenetics in cancer and other diseases. He made the first discoveries of altered DNA methylation in human cancer, discovered human imprinted genes and loss of imprinting (LOI) in cancer, and proved the epigenetic hypothesis of cancer through his research on Beckwith-Wiedemann syndrome. His discovery of epigenetically altered progenitor cells has led to a new understanding of carcinogenesis. As director of the Center for Epigenetics at Johns Hopkins University, he discovered the first evidence of epigenetic mediation of genetic variants in disease. He is currently pursuing a novel model of genetically driven epigenetic plasticity in evolution and disease through an NIH Director’s Pioneer Award.

Feinberg received his bachelor’s, Master of Public Health, and his MD degrees from Johns Hopkins. He completed postdoctoral fellowships at the University of California, San Diego and Johns Hopkins.

Feinberg was a HHMI investigator from 1986–94 while at the University of Michigan before becoming the King Fahd Professor of Molecular Medicine at Johns Hopkins. He is a member of the American Society for Clinical Investigation, the Association of American Physicians, the American Academy of Arts and Sciences, and the Institute of Medicine. He is the recipient of honorary doctorates from Uppsala University and the Karolinska Institutet, both located in Sweden, and from the University of Amsterdam.